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MNPR

Monopar Therapeutics (NASDAQ:MNPR)

US · Delayed Price · Currency is USD
Healthcare · Biotechnology
$72.68+$0.95 (+1.32%)
 
Market cap
$488M
Insider Score
Health Score
Analyst consensus
Listed since
Dec 19, 2019
Market Cap$487.84M-12.0%
Revenue (ttm)$0
Net Income-$6.21B-31846.2%
EPS-$925.32-19.4%
Shares Out6.71M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume313,024
Open$70.11
Previous Close$71.73
Day's Range$67.22 - $74.40
52-Week Range$50.07 - $124.82
Beta1.61
AnalystsBuy
Price Target$126.00(+73.36%)
Earnings DateMar 25, 2027

About MNPR

Monopar Therapeutics Inc., a clinical-stage biopharmaceutical company, engages in developing therapeutics for the treatment of cancer in the United States. The company develops ALXN1840, a late-stage, investigational once-daily and oral medicine; MNPR-101, a proprietary humanized monoclonal antibody that is conjugated with different radioisotopes for the treatment of advanced solid tumors expressing urokinase plasminogen activator receptor; and MNPR-101-Zr, which is in phase 1 imaging and dosimetry clinical trial, a radiopharmaceutical imaging agent comprised of MNPR-101 conjugated to zirconium-89. It develops MNPR-101-Lu, a Phase1a stage radiotherapeutic comprised of MNPR-101 conjugated to actinium-225. The company has collaborations NorthStar to develop radio-immuno-therapeutics targeting severe COVID-19; Excel Diagnostics and Nuclear Oncology Center, for the investigational imaging agent MNPR-101-Zr and investigational therapeutic agent MNPR-101-Lu; license agreement with Alexion to develop and commercialize ALXN1840, a drug candidate for Wilson disease. The company was founded in 2014 and is headquartered in Wilmette, Illinois.

Address
1000 Skokie Boulevard, Wilmette, IL, 60091, US
Market Cap
488 million
Employees
22
Industrial Classification
Biotechnology

What Are Insiders Doing?

Open-market buy / sell balanceNet Selling
Sold
$2.82M
Bought
$0

View the trades behind this meter — each links to its SEC Form 4 →

Open-market Form 4 purchases (code P) vs sales (code S) on file for this company. Grants, option exercises and tax withholdings are excluded. Informational only.

Analyst consensus

Moderate Buy
2 Buy1 Hold0 Sell

3 firms rating MNPR in the last 3 months, one vote each. Issuer-paid research is not counted.

Financial Health Score
Fair
From MNPR’s reported statements · Q3 2026 (trailing 12 months) · 4 of 5 pillars

Next catalysts

1 Day
+1.32%
5 Days
+6.85%
1 Month
-5.67%
6 Months
+18.47%
1 Year
-11.99%

$MNPR stock is featured in our Insider Score Rankings, and Insider Trades datasets.

→ All Stock Lists

Recently reported changes in MNPR holdings by institutional investors

Scanning latest 13F filings…

Latest 0 13F filings · Source: SEC EDGAR

View all institutional owners →

Insider Trading

Quarterly net insider trading by MNPR's directors and management

Net Shares Purchased by Insiders−20k−10k02025Q42026Q12026Q22026Q32026Q4

Source: SEC EDGAR (Form 4)

Corporate Lobbying

MNPR Estimated quarterly lobbying spending

Source: U.S. Senate LDA

U.S. Patents

New MNPR patent grants

Loading patent grants…

Source: USPTO Open Data Portal

Government Contracts

Estimated quarterly amount awarded to MNPR from public contracts

Source: USAspending.gov

Top ETF Holders

ETFs with the largest estimated holdings in MNPR

VTIVanguard Morningstar Total Stock Market ETF$12.73M
XBIState Street SPDR S&P Biotech ETF$10.40M
IWMiShares Russell 2000 ETF$8.49M
VXFVanguard Extended Market ETF$4.26M
IWNiShares Russell 2000 Value ETF$2.28M
VTWOVanguard Russell 2000 ETF$2.09M

Estimated from each fund’s disclosed top holdings × AUM

Bull Case vs Bear Case

AI-generated from MNPR’s recent data — informational, not investment advice

Generating analysis…

What’s Behind the Score

Insider Activity
48% of score
1.07
Analyst Ratings
32% of score
60
News & Sentiment
20% of score
68

News check: Company reporting Q3 results and presenting clinical data for pipeline programs at major medical conference, indicating active development progress.

Recent Insider Activity

Buys
0
Sells
13
Buy Value
$0
Distinct Buyers
0

Insider Score Trend Over Time

-37.0 since Aug 28
0255075100Aug 28 — Insider Score 37.0Aug 29 — Insider Score 36.0Aug 30 — Insider Score 37.0Aug 31 — Insider Score 37.0Sep 1 — Insider Score 0.0Sep 2 — Insider Score 0.0Sep 3 — Insider Score 0.0Sep 4 — Insider Score 0.0Sep 5 — Insider Score 0.0Sep 6 — Insider Score 0.0Sep 7 — Insider Score 0.0Sep 8 — Insider Score 0.0Sep 9 — Insider Score 0.0Sep 10 — Insider Score 0.0Sep 11 — Insider Score 0.0Sep 12 — Insider Score 0.0Sep 13 — Insider Score 0.0Sep 14 — Insider Score 0.0Sep 15 — Insider Score 0.0Sep 16 — Insider Score 0.0Sep 17 — Insider Score 0.0Sep 18 — Insider Score 0.0Sep 19 — Insider Score 0.0Sep 20 — Insider Score 0.0Sep 21 — Insider Score 0.0Sep 22 — Insider Score 0.0Sep 23 — Insider Score 0.0Sep 24 — Insider Score 0.0Sep 25 — Insider Score 0.0Sep 26 — Insider Score 0.0Sep 27 — Insider Score 0.0Sep 28 — Insider Score 0.0Sep 29 — Insider Score 0.0Sep 30 — Insider Score 0.0Oct 1 — Insider Score 0.0Oct 2 — Insider Score 23.0Oct 3 — Insider Score 0.0Oct 4 — Insider Score 0.0Aug 28Sep 15Oct 4

Composite Insider Score (0–100) recomputed on each scoring run from live SEC Form 4 data.

Frequently Asked Questions

Disclaimer — Informational only — not investment advice. Insider transaction data is sourced from SEC Form 4 filings; market data from public feeds and may be delayed. The Insider Score is a proprietary score for research purposes and does not predict future performance. Always do your own research.

ETFs that hold this stock

BBCVirtus Biotech Clinical Trials ETF0.89%
XBIState Street SPDR S&P Biotech ETF0.10%
IWCiShares Micro-Cap ETF0.08%
VFMOVanguard U.S. Momentum Factor ETF0.05%
PWSPacer WealthShield ETF0.02%
LABUDirexion Daily S&P Biotech Bull 3X Shares0.02%

Weight is the stock’s share of each fund’s holdings.