Opko Health, Inc. (NASDAQ:OPK)
| Market Cap | 1.32B+27.3% |
| Revenue (ttm) | 501.64M-21.9% |
| Net Income | -94.52M+47.6% |
| EPS | -0.12+49.2% |
| Shares Out | 746.33M |
| PE Ratio | n/a |
| Forward PE | n/a |
| Dividend | n/a |
| Ex-Dividend Date | n/a |
| Volume | 4,749,980 |
| Open | 1.74 |
| Previous Close | 1.72 |
| Day's Range | 1.74 - 1.80 |
| 52-Week Range | 0.98 - 1.81 |
| Beta | 1.52 |
| Analysts | Buy |
| Price Target | 3.13(+76.84%) |
| Earnings Date | Nov 4, 2026 |
No insider has filed an open-market purchase or sale here in the last 90 days, so there is nothing to score yet.
About OPK
OPKO Health, Inc. operates as a healthcare enterprise with a dual focus on diagnostics and pharmaceuticals. Its operations span the United States, Ireland, Chile, Spain, Israel, Mexico, and other international markets. The company's Diagnostics division encompasses BioReference Laboratories, which delivers a comprehensive suite of laboratory testing services. These services are crucial for disease detection, diagnosis, evaluation, monitoring, and treatment, covering areas such as esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health, and correctional healthcare. BioReference serves a diverse client base, including medical practices, clinics, hospitals, employers, and government entities. Additionally, this segment provides a cutting-edge diagnostic instrument system designed for immediate, point-of-care blood test results, alongside its specialized 4Kscore testing for prostate cancer. Within the Pharmaceutical segment, OPKO offers a range of therapeutic products and a robust development pipeline. Key offerings include Rayaldee, indicated for the management of secondary hyperparathyroidism in adults suffering from stage 3 or 4 chronic kidney disease and vitamin D insufficiency. The pipeline features OPK88004, an investigational orally administered selective androgen receptor modulator; OPK88003, a peptide administered once weekly currently in Phase IIb trials for the treatment of type 2 diabetes and obesity; and hGH-CTP, a once-weekly human growth hormone injection that has successfully completed Phase III clinical trials in collaboration with Pfizer, Inc. A core strategy for this segment involves the development and commercialization of proprietary, extended-release versions of existing therapeutic proteins. Furthermore, OPKO Health supplies specialty active pharmaceutical ingredients (APIs) and is involved in the development, manufacturing, marketing, and sale of pharmaceutical, nutraceutical, veterinary, and ophthalmic products. The company also commercializes food supplements and over-the-counter products, produces and sells items primarily within the generics market, and handles the import, marketing, distribution, and sales of pharmaceutical products across various therapeutic areas, including cardiovascular conditions, vaccines, antibiotics, gastro-intestinal ailments, and hormone-related treatments, among others. Its pharmaceutical operations are further bolstered by platforms situated in Ireland, Chile, Spain, and Mexico. Founded in 1991, OPKO Health, Inc. maintains its corporate headquarters in Miami, Florida.
What Are Insiders Doing?
View the trades behind this meter — each links to its SEC Form 4 →
Open-market Form 4 purchases (code P) vs sales (code S) on file for this company. Grants, option exercises and tax withholdings are excluded. Informational only.
Analyst consensus
2 firms rating OPK in the last 3 months, one vote each. Issuer-paid research is not counted.
Latest investor presentation
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$OPK stock is featured in our Insider Trades datasets.
→ All Stock ListsRecently reported changes in OPK holdings by institutional investors
Latest 0 13F filings · Source: SEC EDGAR
View all institutional owners →Insider Trading
Quarterly net insider trading by OPK's directors and management
Source: SEC EDGAR (Form 4)
Corporate Lobbying
OPK Estimated quarterly lobbying spending
Source: U.S. Senate LDA
OPK Revenue by Segment or Geography
| Segment | Revenue | % of All |
|---|---|---|
| Balance at end | $8.43M | 35.87% |
| Balance at beginning | $8.14M | 34.62% |
| Provision related to current period sales | $6.94M | 29.51% |
As of: Q3 2026 (Sep 30, 2026) · Source: SEC EDGAR (10-Q)
U.S. Patents
New OPK patent grants
Source: USPTO Open Data Portal
Government Contracts
Estimated quarterly amount awarded to OPK from public contracts
Source: USAspending.gov
Top ETF Holders
ETFs with the largest estimated holdings in OPK
| ETF | Est. Holding Size |
|---|---|
| IWMiShares Russell 2000 ETF | $17.43M |
| VTIVanguard Morningstar Total Stock Market ETF | $15.70M |
| VBVanguard Morningstar Small-Cap ETF | $10.82M |
| VXFVanguard Extended Market ETF | $7.69M |
| IWNiShares Russell 2000 Value ETF | $6.39M |
| IBBiShares Biotechnology ETF | $4.78M |
Estimated from each fund’s disclosed top holdings × AUM
OPK Insider Score
Our composite score: insider buying, sector, volume, tone & dilution
Bull Case vs Bear Case
AI-generated from OPK’s recent data — informational, not investment advice
What’s Behind the Score
News check: OPK securing $722M asset sale with analyst upgrade to Outperform and $2.25 PT provides concrete positive catalysts despite valuation debate.
