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Castle Biosciences Inc (NASDAQ:CSTL)

US · Delayed Price · Currency is USD
32.44-0.56 (-1.68%)
 
Market Cap991.15M+37.7%
Revenue (ttm)357.28M+3.2%
Net Income-19.41M-105.1%
EPS-0.66-86.1%
Shares Out30.55M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume9,596.978
Open32.54
Previous Close33.00
Day's Range32.29 - 32.73
52-Week Range17.72 - 44.28
Beta0.94
AnalystsBuy
Price Target39.00(+20.21%)
Earnings DateNov 2, 2026
-1.70% (1D)
No price history available.
Insider Score
––Not scored
CSTL Insider Score

Insiders filed in the last 90 days, but none of those trades qualified for scoring — round-trip buys and filings whose price is far off the market are excluded.

About CSTL

Castle Biosciences, Inc. functions as a commercial-stage diagnostics firm, with its primary objective being the provision of both diagnostic and prognostic testing services, specifically targeting various dermatological cancers. Their flagship product, DecisionDx-Melanoma, represents an advanced multi-gene expression profile (GEP) assay engineered to assess the probability of metastasis in patients afflicted with invasive cutaneous melanoma. In addition to their leading solution, the company has created several other specialized, proprietary tests. Among these is DecisionDx-UM, a GEP test tailored to forecast the risk of metastasis for individuals with uveal melanoma, a less common malignancy of the eye. Another key offering is DecisionDx-SCC, a distinctive 40-gene expression profile test that utilizes a patient's unique tumor biology to predict their specific risk of squamous cell carcinoma metastasis, particularly for those presenting with recognized risk factors. Moreover, they offer DecisionDx DiffDx-Melanoma and myPath Melanoma, both proprietary GEP tests employed to assist in the accurate diagnosis of ambiguous pigmented lesions. These specialized testing services are provided by Castle Biosciences to patients predominantly through their healthcare providers. The organization commenced operations in 2007 and maintains its corporate headquarters in Friendswood, Texas.

Address
1500 W. Parkwood Ave, Friendswood, TX, 77546, US
Market Cap
991 million
Employees
1,002
Industrial Classification
Medical - Diagnostics & Research

What Are Insiders Doing?

Open-market buy / sell balanceNet Selling
Sold
$2.83M
Bought
$0

View the trades behind this meter — each links to its SEC Form 4 →

Open-market Form 4 purchases (code P) vs sales (code S) on file for this company. Grants, option exercises and tax withholdings are excluded. Informational only.

1 Day
-1.59%
5 Days
-8.68%
1 Month
-0.87%
6 Months
+28.92%
1 Year
+37.66%

$CSTL stock is featured in our Insider Score Rankings, Congress Trading, and Insider Trades datasets.

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Congress Trading

Recent trades of CSTL by members of U.S. Congress

PoliticianTypeTraded
Gilbert Ray CisnerosHouse / DPurchase$1.00K – $15.00KDec 23, 2020
Gilbert CisnerosHouse / DPurchase$1.00K – $15.00KDec 23, 2020
Gilbert Ray CisnerosHouse / DPurchase$1.00K – $15.00KDec 22, 2020

Recently reported changes in CSTL holdings by institutional investors

Scanning latest 13F filings…

Latest 0 13F filings · Source: SEC EDGAR

View all institutional owners →

Insider Trading

Quarterly net insider trading by CSTL's directors and management

Net Shares Purchased by Insiders−70k−35k02025Q42026Q12026Q22026Q32026Q4

Source: SEC EDGAR (Form 4)

Corporate Lobbying

CSTL Estimated quarterly lobbying spending

Source: U.S. Senate LDA

CSTL Revenue by Segment

$103.55MTotal
SegmentRevenue% of All
Non-Dermatologic$54.84M52.96%
Dermatologic$48.70M47.04%

As of: Q2 2026 (Jun 30, 2026) · Source: SEC EDGAR (10-Q)

U.S. Patents

New CSTL patent grants

Loading patent grants…

Source: USPTO Open Data Portal

Government Contracts

Estimated quarterly amount awarded to CSTL from public contracts

Source: USAspending.gov

Top ETF Holders

ETFs with the largest estimated holdings in CSTL

ETFEst. Holding Size
VTIVanguard Morningstar Total Stock Market ETF$28.16M
IWMiShares Russell 2000 ETF$26.11M
VXFVanguard Extended Market ETF$11.60M
IWNiShares Russell 2000 Value ETF$9.20M
DFASDimensional - US Small Cap ETF$7.54M
IBBiShares Biotechnology ETF$7.50M

Estimated from each fund’s disclosed top holdings × AUM

CSTL Insider Score

Our composite score: insider buying, sector, volume, tone & dilution

Members only

The live Insider Score for CSTL is included with Insider Access.

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Bull Case vs Bear Case

AI-generated from CSTL’s recent data — informational, not investment advice

Generating analysis…

Insider Score

Our 0–100 Insider Score and the signals behind it.

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Recent Insider Activity

Buys
0
Sells
25
Buy Value
$0
Distinct Buyers
0

Frequently Asked Questions

Disclaimer — Informational only — not investment advice. Insider transaction data is sourced from SEC Form 4 filings; market data from public feeds and may be delayed. The Insider Score is a proprietary score for research purposes and does not predict future performance. Always do your own research.