Key points
- BLSM leads with $25.2M in insider purchases and a Very Strong Insider Score band, signaling exceptional conviction.
- PNAQ saw $29.8M in insider buying activity despite being a SPAC, reflecting high insider confidence.
- Four of the top five are healthcare-focused, suggesting concentrated insider optimism in the life sciences sector.
A high Insider Score doesn't guarantee returns—but it often signals that company insiders believe the stock is undervalued or poised for near-term upside. When multiple insiders across different roles buy heavily within the same quarter, it may suggest management has conviction about future results. Here are the five stocks with the strongest insider conviction signals right now, ranked by our Insider Score feed.
1. BLSM — $25.2M in Insider Buying, Very Strong Conviction
BlossomHill Therapeutics leads our top-five list with $25.1M in total insider purchases and a Very Strong Insider Score band. This level of concentrated buying—particularly across multiple insiders in a therapeutic development company—may suggest leadership sees significant value ahead. The scale of these purchases historically correlates with insider confidence in pipeline progression or clinical trial outcomes.
2. PNAQ — $29.8M Insider Accumulation in SPAC
Pinnacle Acquisition Corp attracted $29.8M in insider buying activity, placing it second despite being a blank-check entity. Such large founder and insider commitments in a SPAC structure may indicate a high-conviction deal target or meaningful sponsor conviction. Investors may want to monitor PNAQ for near-term merger announcements or sponsor confidence signals.
3. TLSA — Biotech Buy-In with Very Strong Score
Tiziana Life Sciences recorded $1.04M in insider purchases alongside a Very Strong Insider Score band. While the dollar volume is lower than the top two picks, the score classification and healthcare sector focus align with broader insider appetite for clinical-stage therapeutics. This combination may suggest management views the current valuation as attractive relative to clinical potential.
4. MDXH — $1M Buy Signal in Diagnostics
MDxHealth SA saw $1.0M in insider purchases with a Strong Insider Score band. The diagnostic-focused healthcare player attracted meaningful insider interest, which may reflect confidence in oncology testing or related products. Diagnostic companies with insider support often trade on clinical adoption cycles—investors may want to track their earnings announcements and partnership news.
5. NTHI — Pharma Insider Support
NEONC TECHNOLOGIES HOLDINGS rounded out the top five with $458K in insider purchases and a Strong Insider Score band. While the purchase size is the smallest on this list, the pharmaceutical sector focus and positive Insider Score may suggest selective insider confidence. Smaller buys can still signal conviction, particularly in early-stage or turnaround situations.
The Bottom Line
These five stocks represent the highest Insider Score signals in our current feed—a mix of Very Strong and Strong conviction bands concentrated heavily in healthcare and life sciences. To explore the full ranked list of insider-buying signals and filter by sector, score band, or purchase size, visit our live Insider Score rankings.