Key points
- BLSM (BlossomHill Therapeutics) carries a Very Strong Insider Score, with insiders purchasing $25.2M in stock.
- PNAQ (Pinnacle Acquisition Corp) insiders committed $29.8M despite being in the SPAC/acquisition phase.
- Four of the top five are healthcare-focused, reflecting sector conviction among institutional insiders.
When insiders buy heavily and consistently, it historically signals confidence in a company's near-term direction and long-term value. Our Insider Score feed tracks the depth and timing of insider purchases, accumulation patterns, and alignment between executives and the companies they lead. The five stocks listed below rank highest on that composite score right now — meaning insiders are putting real money behind conviction.
1. BLSM — Very Strong Conviction in a Healthcare Play
BlossomHill Therapeutics (BLSM) carries a Very Strong Insider Score — the highest band on our scale. Insiders have accumulated over $25.1M in purchases, reflecting sustained, multi-executive buying over time. This level of concentrated insider capital deployment may suggest leadership is confident in clinical progress, product timelines, or the company's strategic positioning in the biotech space.
2. PNAQ — Acquisition-Phase Conviction
Pinnacle Acquisition Corp (PNAQ) insiders have purchased $29.8M in stock, the second-largest total in this top-five list. Even during an active acquisition or blank-check phase, this level of insider commitment may indicate confidence in the target company or deal terms. A Strong Insider Score here historically correlates with insider alignment ahead of a major corporate event.
3. TLSA — Biotech Accumulation Signal
Tiziana Life Sciences Ltd (TLSA) carries a Strong Insider Score with $1.04M in insider purchases. The company operates in the healthcare/biotech space, where insider buying often reflects conviction in clinical trial outcomes or upcoming data releases. This level of activity may warrant monitoring for catalysts over the coming quarters.
4. FEMY — Early-Stage Buying Conviction
FEMASYS INC (FEMY) insiders have purchased $134K with a Strong Insider Score. While smaller in absolute dollars, insider buying at any level in earlier-stage healthcare companies can be a meaningful signal of internal confidence, especially if it represents executives' personal capital with meaningful skin in the game.
5. NTHI — Pharma Preparations Insider Alignment
NEONC Technologies Holdings, Inc. (NTHI) rounds out the top five with a Strong Insider Score and $458.4K in insider purchases. The pharmaceutical preparations sector historically sees insider activity tied to pipeline progress or regulatory milestones, making this accumulation worth tracking alongside company disclosures.
The Bottom Line
High Insider Scores reflect patterns of conviction — multiple insiders buying, sustained over time, with meaningful dollar commitments. These five stocks stand out for that sustained, visible commitment from leadership and major shareholders. To see the full live rankings of stocks by Insider Score and compare these picks with broader market activity, visit our Insider Score rankings page.