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PILL Direxion Daily Pharmaceutical & Medical Bull 3X ETF

Issuer
Direxion
Inception
Nov 15, 2017
AUM
$19.8M
Expense ratio
1.22%
Yield
0.38%
Asset class
Equity
Holdings
50
Last price
$15.58

PILL seeks to deliver investment results of 3x the daily performance of the S&P Pharmaceuticals Select Industry Index, a modified equal-weighted index that measures the performance of pharmaceutical companies, as defined by GICS, on the S&P Total Market Index. The fund uses derivatives and swaps to achieve its target exposure. As a levered product with daily resets, PILL is designed as a short-term trading tool and not a long-term investment vehicle. As a result, long-term returns could materially differ from those of the underlying index due to daily compounding. Prior to August 2, 2019, the fund aimed to provide 3x leveraged exposure to the Dynamic Pharmaceutical Intellidex Index. Effective February 27, 2026, the fund replaced the term Shares in its name with ETF.

+75.9%
2025-11-13low 8.92 · high 23.882026-11-13

Performance

1M3MYTD1Y3Y ann.5Y ann.
PILL+14.7%-26.1%+27.9%+73.7%+46.4%-4.9%
Equity average (4725 funds)-2.2%-4.7%+3008.3%+1886.0%+15.1%+2.6%

Insider activity in the holdings

Open-market insider buying across this fund’s holdings over 90 days, weighted by holding weight: +$52K net.

HoldingWeightInsiders boughtInsiders sold
RAPP RAPPORT THERAPEUTICS INC0.16%$22.0M$4.5M
ALMS ALUMIS INC0.19%$10.7M$1.0M
RLMD RELMADA THERAPEUTICS INC0.16%$1.7M$0
ELAN ELANCO ANIMAL HEALTH INC0.32%$1.0M$100K
AQST AQUESTIVE THERAPEUTICS INC0.13%$99K$379K
EYPT EYEPOINT INC0.01%$52K$0
LXRX LEXICON PHARMACEUTICALS INC0.12%$50K$0

Holdings · as of Nov 13, 2026

#HoldingWeight
1PILL SPSIPH SWAP ASSET LEG (SPSIPHBCL)29.22%
2XERS XERIS BIOPHARMA HOLDINGS INC0.61%
3MANE VERADERMICS INC0.45%
4MAZE MAZE THERAPEUTICS INC0.38%
5LLY ELI LILLY & CO0.36%
6VTRS VIATRIS INC0.36%
7PCRX PACIRA BIOSCIENCES INC0.36%
8AMRX AMNEAL PHARMACEUTICALS INC0.36%
9SEPN SEPTERNA INC0.34%
10ETON ETON PHARMACEUTICALS INC0.33%
11RPRX ROYALTY PHARMA PLC- CL A0.33%
12PRGO PERRIGO CO PLC0.33%
13ZTS ZOETIS INC0.32%
14ELAN ELANCO ANIMAL HEALTH INC0.32%
15LGND LIGAND PHARMACEUTICALS0.31%
16EWTX EDGEWISE THERAPEUTICS INC0.31%
17PFE PFIZER INC0.30%
18JNJ JOHNSON & JOHNSON0.30%
19COLL COLLEGIUM PHARMACEUTICAL INC0.29%
20JAZZ JAZZ PHARMACEUTICALS PLC0.29%
21OGN ORGANON & CO0.29%
22ANIP ANI PHARMACEUTICALS INC0.29%
23MRK MERCK & CO. INC.0.28%
24AMLX AMYLYX PHARMACEUTICALS INC0.28%
25BMY BRISTOL-MYERS SQUIBB CO0.28%
26OMER OMEROS CORP0.27%
27TARS TARSUS PHARMACEUTICALS INC0.26%
28MBX MBX BIOSCIENCES INC0.26%
29DFTX DEFINIUM THERAPEUTICS INC0.26%
30PBH PRESTIGE CONSUMER HEALTHCARE0.26%
31INVA INNOVIVA INC0.25%
32ELVN ENLIVEN THERAPEUTICS INC0.25%
33TRVI TREVI THERAPEUTICS INC0.25%
34AMPH AMPHASTAR PHARMACEUTICALS IN0.24%
35SUPN SUPERNUS INC0.24%
36ZVRA ZEVRA THERAPEUTICS INC0.24%
37HRMY HARMONY BIOSCIENCES HOLDINGS0.23%
38LBRX LB PHARMACEUTICALS INC0.23%
39LQDA LIQUIDIA CORP0.23%
40HROW HARROW INC0.22%
41ANRO ALTO NEUROSCIENCE INC0.21%
42AXSM AXSOME THERAPEUTICS INC0.20%
43ALMS ALUMIS INC0.19%
44NUVB NUVATION BIO INC0.19%
45CORT CORCEPT THERAPEUTICS INC0.18%
46WVE WAVE LIFE SCIENCES INC0.18%
47OCUL OCULAR THERAPEUTIX INC0.16%
48PAHC PHIBRO ANIMAL HEALTH CORP-A0.16%
49RAPP RAPPORT THERAPEUTICS INC0.16%
50RLMD RELMADA THERAPEUTICS INC0.16%
51PHAT PHATHOM PHARMACEUTICALS INC0.14%
52ACRS ACLARIS THERAPEUTICS INC0.14%
53AVLN AVALYN PHARMA INC0.13%
54AQST AQUESTIVE THERAPEUTICS INC0.13%
55CRMD CORMEDIX INC0.12%
56LXRX LEXICON PHARMACEUTICALS INC0.12%
57ARVN ARVINAS INC0.10%
58EOLS EVOLUS INC0.10%
59BIOA BIOAGE LABS INC0.08%
60CTNM CONTINEUM THERAPEUTICS INC-A0.07%
61EYPT EYEPOINT INC0.01%

Sector breakdown

Healthcare100.0%

Country breakdown

United States100.0%

Distributions

DatePer unit
Sep 22, 2026$0.0009
Jun 23, 2026$0.0152
Mar 24, 2026$0.0109
Dec 23, 2025$0.0326
Sep 23, 2025$0.0098
Jun 24, 2025$0.0245
Mar 25, 2025$0.0183
Dec 23, 2024$0.0131
Sep 24, 2024$0.0287
Jun 25, 2024$0.0219
Mar 19, 2024$0.0272
Dec 21, 2023$0.0382
Sep 19, 2023$0.0353
Jun 21, 2023$0.0492
Mar 21, 2023$0.0191
Dec 20, 2022$0.0317
Sep 20, 2022$0.0167
Jun 22, 2022$0.0036
Mar 22, 2022$0.0082
Dec 21, 2021$0.0001
Dec 23, 2019$0.0003
Sep 24, 2019$0.0152
Jun 25, 2019$0.0224
Mar 19, 2019$0.0573
Dec 27, 2018$0.0986
Sep 25, 2018$0.0434
Jun 19, 2018$0.0523
Dec 19, 2017$0.0135

Members of Congress who disclosed this ETF

No member of Congress has disclosed a trade in PILL in the filings we hold.

Fund facts, prices, performance and distributions: our market-data vendor. Holdings: the vendor and SEC Form N-PORT. Insider and Congress data: InsiderBuying. Last updated Nov 13, 2026. This is historical data, not investment advice. Report a data error

PILL: Direxion Daily Pharmaceutical & Medical Bull 3X ETF — Holdings, Performance and Insider Activity | InsiderBuying.com