PBE Invesco Biotechnology & Genome ETF
The Invesco Biotechnology & Genome ETF (PBE) seeks to replicate the performance of the Dynamic Biotech & Genome Intellidex Index. This fund typically allocates a minimum of 90% of its total assets to the securities comprising the underlying index. The Index is constructed to achieve capital appreciation by thoroughly evaluating companies based on several investment criteria, including their price momentum, earnings growth, overall quality, management decisions, and valuation. It consists of 30 U.S.-based companies within the biotechnology and genome sectors. These companies are primarily involved in the research, development, manufacture, and distribution of various biotechnological products, services, and processes, or they are businesses that stand to gain significantly from scientific and technological breakthroughs in biotechnology and genetic engineering. Both the ETF and its benchmark index undergo quarterly rebalancing and reconstitution in February, May, August, and November.
Performance
| 1M | 3M | YTD | 1Y | 3Y ann. | 5Y ann. | |
|---|---|---|---|---|---|---|
| PBE | +2.6% | +3.4% | +18.6% | +25.5% | +21.7% | +6.3% |
| Equity average (4725 funds) | -2.1% | +2.6% | +2746.7% | +63010.1% | +11.7% | +1.4% |
Insider activity in the holdings
Open-market insider buying across this fund’s holdings over 90 days, weighted by holding weight: +$0 net.
No open-market insider buys in the holdings in the last 90 days.
Holdings · as of Nov 12, 2026
| # | Holding | Weight |
|---|---|---|
| 1 | REGN Regeneron Pharmaceuticals Inc | 5.66% |
| 2 | BIIB Biogen Inc | 5.64% |
| 3 | GILD Gilead Sciences Inc | 5.61% |
| 4 | RPRX Royalty Pharma PLC | 5.55% |
| 5 | AMGN Amgen Inc | 5.20% |
| 6 | VRTX Vertex Pharmaceuticals Inc | 4.86% |
| 7 | NTRA Natera Inc | 4.67% |
| 8 | ILMN Illumina Inc | 4.65% |
| 9 | MRNA Moderna Inc | 4.20% |
| 10 | VCEL Vericel Corp | 3.69% |
| 11 | EXEL Exelixis Inc | 3.34% |
| 12 | TGTX TG Therapeutics Inc | 3.18% |
| 13 | QGEN QIAGEN NV | 3.09% |
| 14 | UTHR United Therapeutics Corp | 3.08% |
| 15 | NBIX Neurocrine Biosciences Inc | 3.05% |
| 16 | NVAX Novavax Inc | 2.84% |
| 17 | RGEN Repligen Corp | 2.55% |
| 18 | INCY Incyte Corp | 2.53% |
| 19 | HALO Halozyme Therapeutics Inc | 2.49% |
| 20 | LEGN Legend Biotech Corp | 2.46% |
| 21 | COLL Collegium Pharmaceutical Inc | 2.42% |
| 22 | PTGX Protagonist Therapeutics Inc | 2.40% |
| 23 | PTCT PTC Therapeutics Inc | 2.37% |
| 24 | BMRN BioMarin Pharmaceutical Inc | 2.37% |
| 25 | SRPT Sarepta Therapeutics Inc | 2.36% |
| 26 | ANAB AnaptysBio Inc | 2.24% |
| 27 | ARDX Ardelyx Inc | 2.22% |
| 28 | BCRX BioCryst Pharmaceuticals Inc | 2.09% |
| 29 | ACAD ACADIA Pharmaceuticals Inc | 1.61% |
| 30 | VCYT Veracyte Inc | 1.53% |
| 31 | AGPXX Invesco Government & Agency Portfolio | 0.04% |
| 32 | PBE CASH & EQUIVALENTS | 0.00% |
Sector breakdown
Country breakdown
Distributions
| Date | Per unit |
|---|---|
| Sep 21, 2026 | $0.0187 |
| Jun 22, 2026 | $0.8106 |
| Mar 23, 2026 | $0.0824 |
| Dec 22, 2025 | $0.4197 |
| Sep 22, 2025 | $0.2341 |
| Jun 23, 2025 | $0.1305 |
| Mar 24, 2025 | $0.0341 |
| Jun 24, 2024 | $0.0082 |
| Mar 18, 2024 | $0.0242 |
| Jun 20, 2023 | $0.0141 |
| Mar 23, 2020 | $0.0290 |
| Sep 24, 2018 | $0.0021 |
| Jun 16, 2017 | $0.2153 |
| Mar 17, 2017 | $0.0555 |
| Dec 16, 2016 | $0.1208 |
| Sep 16, 2016 | $0.0283 |
| Dec 18, 2015 | $0.3082 |
| Sep 18, 2015 | $0.1366 |
| Jun 19, 2015 | $0.1227 |
| Sep 19, 2014 | $0.0429 |
| Jun 20, 2014 | $0.2340 |
| Dec 18, 2009 | $0.0755 |
Members of Congress who disclosed this ETF
No member of Congress has disclosed a trade in PBE in the filings we hold.
Fund facts, prices, performance and distributions: our market-data vendor. Holdings: the vendor and SEC Form N-PORT. Insider and Congress data: InsiderBuying. Last updated Nov 13, 2026. This is historical data, not investment advice. Report a data error
