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IHE iShares U.S. Pharmaceuticals ETF

Issuer
IShares
Inception
May 1, 2006
AUM
$1.7B
Expense ratio
0.37%
Yield
1.30%
Asset class
Equity
Holdings
52
Last price
$109.92

The iShares U.S. Pharmaceuticals ETF is designed to replicate the investment performance of a benchmark index. This index consists solely of equity securities from pharmaceutical companies operating within the United States.

+37.7%
2025-11-13low 80.25 · high 111.082026-11-13

Performance

1M3MYTD1Y3Y ann.5Y ann.
IHE+10.5%+7.4%+30.8%+39.3%+25.9%+12.9%
Equity average (4725 funds)-2.2%-4.7%+3008.3%+1886.0%+15.1%+2.6%

Insider activity in the holdings

Open-market insider buying across this fund’s holdings over 90 days, weighted by holding weight: +$78K net.

HoldingWeightInsiders boughtInsiders sold
RAPP RAPPORT THERAPEUTICS0.24%$22.0M$4.5M
ALMS ALUMIS0.12%$10.7M$1.0M
ELAN ELANCO ANIMAL HEALTH2.68%$1.0M$100K
EYPT EYEPOINT INC0.01%$52K$0

Holdings · as of Nov 12, 2026

#HoldingWeight
1LLY ELI LILLY26.45%
2JNJ JOHNSON & JOHNSON21.72%
3VTRS VIATRIS4.90%
4RPRX ROYALTY PHARMA PLC CLASS A4.78%
5ZTS ZOETIS INC CLASS A4.66%
6PFE PFIZER4.39%
7MRK MERCK & CO INC4.13%
8BMY BRISTOL MYERS SQUIBB4.04%
9JAZZ JAZZ PHARMACEUTICALS PLC3.26%
10ELAN ELANCO ANIMAL HEALTH2.68%
11CORT CORCEPT THERAPEUTICS1.44%
12AXSM AXSOME THERAPEUTICS1.35%
13LGND LIGAND PHARMACEUTICALS1.28%
14SUPN SUPERNUS1.24%
15MANE VERADERMICS0.99%
16DFTX DEFINIUM THERAPEUTICS INC0.94%
17LQDA LIQUIDIA0.83%
18AMRX AMNEAL PHARMACEUTICALS INC CLASS A0.81%
19EWTX EDGEWISE THERAPEUTICS0.79%
20OGN ORGANON0.74%
21AMLX AMYLYX PHARMACEUTICALS0.66%
22ELVN ENLIVEN THERAPEUTICS0.66%
23XERS XERIS BIOPHARMA HOLDINGS0.61%
24TARS TARSUS PHARMACEUTICALS0.60%
25PRGO PERRIGO PLC0.47%
26PBH PRESTIGE CONSUMER HEALTHCARE0.42%
27TRVI TREVI THERAPEUTICS0.36%
28MBX MBX BIOSCIENCES0.35%
29HRMY HARMONY BIOSCIENCES HLDG0.34%
30PCRX PACIRA BIOSCIENCES0.29%
31ANIP ANI PHARMACEUTICALS0.29%
32INVA INNOVIVA0.28%
33MAZE MAZE THERAPEUTICS0.27%
34OMER OMEROS0.27%
35OCUL OCULAR THERAPEUTIX0.25%
36RAPP RAPPORT THERAPEUTICS0.24%
37SEPN SEPTERNA0.23%
38NUVB NUVATION BIO CLASS A0.23%
39LBRX LB PHARMACEUTICALS INC0.23%
40HROW HARROW0.19%
41AMPH AMPHASTAR PHARMACEUTICALS0.18%
42COLL COLLEGIUM PHARMACEUTICAL0.16%
43PAHC PHIBRO ANIMAL HEALTH CORP CLASS A0.15%
44ALMS ALUMIS0.12%
45AVLN AVALYN PHARMA INC0.11%
46IHE USD CASH0.11%
47WVE WAVE LIFE SCIENCES0.10%
48EOLS EVOLUS INC0.09%
49ARVN ARVINAS0.08%
50PHAT PHATHOM PHARMACEUTICALS0.07%
51CRMD CORMEDIX0.07%
52BIOA BIOAGE LABS0.05%
53EYPT EYEPOINT INC0.01%

Sector breakdown

Pharmaceuticals99.9%
Cash and/or Derivatives0.1%

Country breakdown

United States100.0%

Distributions

DatePer unit
Sep 15, 2026$0.2789
Jun 15, 2026$0.2848
Mar 17, 2026$0.2845
Dec 16, 2025$0.5853
Sep 16, 2025$0.3124
Jun 16, 2025$0.3065
Mar 18, 2025$0.2917
Dec 17, 2024$0.2108
Sep 25, 2024$0.3589
Jun 11, 2024$0.2940
Mar 21, 2024$0.2750
Dec 20, 2023$0.1347
Sep 26, 2023$0.3007
Jun 7, 2023$0.1967
Mar 23, 2023$0.2240
Dec 13, 2022$0.4457
Sep 26, 2022$0.2949
Jun 9, 2022$0.2390
Mar 24, 2022$0.2647
Dec 13, 2021$0.2633
Sep 24, 2021$0.2773
Jun 10, 2021$0.2403
Mar 25, 2021$0.2117
Dec 14, 2020$0.1753
Sep 23, 2020$0.2363
Jun 15, 2020$0.1047
Mar 25, 2020$0.1957
Dec 16, 2019$0.1717
Sep 24, 2019$0.2098
Jun 17, 2019$0.1783
Mar 20, 2019$0.1857
Dec 17, 2018$0.1168
Sep 26, 2018$0.1321
Jun 26, 2018$0.1628
Mar 22, 2018$0.1767
Dec 19, 2017$0.1242
Sep 26, 2017$0.1498
Jun 27, 2017$0.3061
Mar 24, 2017$0.1193
Dec 21, 2016$0.1127

Members of Congress who disclosed this ETF

MemberActionAmount bandDate
Bill Cassidy · Senate · RSell$1K–$15KJan 31, 2018
Bill Cassidy · Senate · RBuy$1K–$15KAug 27, 2015

Fund facts, prices, performance and distributions: our market-data vendor. Holdings: the vendor and SEC Form N-PORT. Insider and Congress data: InsiderBuying. Last updated Nov 13, 2026. This is historical data, not investment advice. Report a data error

IHE: iShares U.S. Pharmaceuticals ETF — Holdings, Performance and Insider Activity | InsiderBuying.com