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Spyre Therapeutics, Inc. (NASDAQ:SYRE)
US · Delayed Price · Currency is USD
Also listed: AGLEHealthcare · Biotechnology
92.91+2.58 (+2.86%)
Insider Score
––Not scored
SYRE Insider Score
Insiders filed in the last 90 days, but none of those trades qualified for scoring — round-trip buys and filings whose price is far off the market are excluded.
SYRE Stock Insider Trading Activity
SYRE stock’s insider trading shows 23 sales on the open market for an estimated $8.61M by company insiders over the last 6 months.
Not enough price history.
Insider Trading Activity (Form 4 Filings)
An insider trade occurs when an individual that has non-public information about a company buys or sells shares of that company’s stock. Examples of insiders include a company’s executive officers (CEO, CFO, COO), its board of directors, and its major shareholders. Insiders are required to submit their trading activity to the SEC through Form 4 filings.
Scored window · last 90 days0 qualifying buys0 insiders$0 bought— these are the numbers in the rankings table; the full history below shows every filing (buys, sells and older activity).
| Insider | Action | Shares | Avg Cost | Total | Δ Holdings | Held After | Date | Grade | Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| Turtle Cameron CEO | Sell | 3,989 | $92.31 | $368.22K | 0.7% | 542,630 | Oct 1, 2026 | — | Form 4 |
| Turtle Cameron CEO | Sell | 2,683 | $90.10 | $241.74K | 0.5% | 549,257 | Oct 1, 2026 | — | Form 4 |
| Turtle Cameron CEO | Sell | 600 | $89.14 | $53.48K | 0.1% | 551,940 | Oct 1, 2026 | — | Form 4 |
| King-Jones Heidy Other | Sell | 2,600 | $93.46 | $243.00K | 47.8% | 2,845 | Oct 1, 2026 | — | Form 4 |
| King-Jones Heidy Other | Sell | 2,100 | $92.70 | $194.67K | 27.8% | 5,445 | Oct 1, 2026 | — | Form 4 |
| King-Jones Heidy Other | Sell | 7,228 | $91.35 | $660.28K | 48.9% | 7,545 | Oct 1, 2026 | — | Form 4 |
| King-Jones Heidy Other | Sell | 16,605 | $90.35 | $1.50M | 52.9% | 14,773 | Oct 1, 2026 | — | Form 4 |
| King-Jones Heidy Other | Option exercise | 28,933 | $14.50 | $419.53K | 1017% | 31,778 | Oct 1, 2026 | — | Form 4 |
| King-Jones Heidy Other | Sell | 400 | $89.24 | $35.70K | 1.3% | 31,378 | Oct 1, 2026 | — | Form 4 |
| Burrows Scott L CFO | Sell | 229 | $93.57 | $21.43K | 0.3% | 79,762 | Oct 1, 2026 | — | Form 4 |
| Burrows Scott L CFO | Sell | 3,071 | $92.95 | $285.45K | 3.7% | 79,991 | Oct 1, 2026 | — | Form 4 |
| Burrows Scott L CFO | Sell | 2,100 | $91.92 | $193.03K | 2.5% | 83,062 | Oct 1, 2026 | — | Form 4 |
| Burrows Scott L CFO | Sell | 600 | $89.07 | $53.44K | 0.7% | 86,662 | Oct 1, 2026 | — | Form 4 |
| Burrows Scott L CFO | Option exercise | 7,500 | $14.50 | $108.75K | 9.4% | 87,262 | Oct 1, 2026 | — | Form 4 |
| Turtle Cameron CEO | Sell | 100 | $93.91 | $9.39K | 0.0% | 537,540 | Oct 1, 2026 | — | Form 4 |
| Turtle Cameron CEO | Sell | 4,990 | $93.37 | $465.92K | 0.9% | 537,640 | Oct 1, 2026 | — | Form 4 |
| Turtle Cameron CEO | Sell | 2,638 | $91.49 | $241.35K | 0.5% | 546,619 | Oct 1, 2026 | — | Form 4 |
| Burrows Scott L CFO | Sell | 1,500 | $90.27 | $135.41K | 1.7% | 85,162 | Oct 1, 2026 | — | Form 4 |
| Burrows Scott L CFO | Option exercise | 17,500 | $14.50 | $253.75K | 21.9% | 97,262 | Sep 30, 2026 | — | Form 4 |
| Burrows Scott L CFO | Sell | 17,500 | $89.89 | $1.57M | 18.0% | 79,762 | Sep 30, 2026 | — | Form 4 |
| Burrows Scott L CFO | Sell | 18,232 | $89.35 | $1.63M | 18.6% | 79,762 | Sep 2, 2026 | — | Form 4 |
| King-Jones Heidy Other | Sell | 400 | $90.00 | $36.00K | 12.3% | 2,845 | Sep 2, 2026 | — | Form 4 |
| King-Jones Heidy Other | Option exercise | 400 | $14.50 | $5.80K | 14.1% | 3,245 | Sep 2, 2026 | — | Form 4 |
| Turtle Cameron CEO | Sell | 400 | $89.07 | $35.63K | 0.1% | 552,540 | Sep 1, 2026 | — | Form 4 |
| Burrows Scott L CFO | Option exercise | 7,500 | $14.50 | $108.75K | 7.7% | 105,494 | Sep 1, 2026 | — | Form 4 |
| Burrows Scott L CFO | Sell | 900 | $86.25 | $77.63K | 0.9% | 104,594 | Sep 1, 2026 | — | Form 4 |
| Burrows Scott L CFO | Sell | 4,384 | $87.11 | $381.89K | 4.2% | 100,210 | Sep 1, 2026 | — | Form 4 |
| Burrows Scott L CFO | Sell | 2,016 | $88.03 | $177.47K | 2.0% | 98,194 | Sep 1, 2026 | — | Form 4 |
What these mean— the action is the SEC’s own Form 4 transaction code. Only a buy or a sell is an open-market trade; the rest are transfers, awards and exercises, which is why they carry no price.
- Sell (S) — Open-market or private sale
- Option exercise (M) — Exercise or conversion of an exempt derivative
Disclaimer — Informational only — not investment advice. Insider transaction data is sourced from SEC Form 4 filings; market data from public feeds and may be delayed. The Insider Score is a proprietary score for research purposes and does not predict future performance. Always do your own research.