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Krystal Biotech, Inc. (NASDAQ:KRYS)

US · Delayed Price · Currency is USD
324.57-2.24 (-0.69%)
 
Market Cap9.57B+73.4%
Revenue (ttm)440.48M+22.6%
Net Income241.47M+64.6%
EPS7.98+62.2%
Shares Out29.48M
PE Ratio39.25
Forward PE34.71
Dividendn/a
Ex-Dividend Daten/a
Volume354,149
Open324.87
Previous Close326.81
Day's Range320.19 - 330.44
52-Week Range179.19 - 382.54
Beta0.50
AnalystsBuy
Price Target395.20(+21.76%)
Earnings DateNov 2, 2026
Insider Score
––Not scored
KRYS Insider Score

Insiders filed in the last 90 days, but none of those trades qualified for scoring — round-trip buys and filings whose price is far off the market are excluded.

About KRYS

Krystal Biotech, Inc. is a clinical-stage biotechnology company focused on developing redosable gene therapies to address severe orphan diseases across the United States. Its most advanced therapeutic candidate, beremagene geperpavec (B-VEC), is currently undergoing Phase III clinical evaluation for the treatment of dystrophic epidermolysis bullosa. The company's pipeline also includes several other promising programs: KB105 is in Phase I/II clinical trials for patients suffering from deficient autosomal recessive congenital ichthyosis; KB301 is also in Phase I/II development, aiming to ameliorate wrinkles and other signs of aging or damaged skin. Additionally, Krystal Biotech is conducting preclinical research on KB407 for cystic fibrosis and KB104 for Netherton syndrome. In its earlier discovery phase, the company is exploring candidates such as KB5xx for chronic skin conditions and multiple KB3xx programs targeting aesthetic dermatological concerns. Krystal Biotech, Inc. was established in 2015 and is based in Pittsburgh, Pennsylvania.

Address
2100 Wharton Street, Pittsburgh, PA, 15203, US
Market Cap
9.57 billion
Employees
295
Industrial Classification
Biotechnology

What Are Insiders Doing?

Open-market buy / sell balanceNet Selling
Sold
$23.54M
Bought
$0

View the trades behind this meter — each links to its SEC Form 4 →

Open-market Form 4 purchases (code P) vs sales (code S) on file for this company. Grants, option exercises and tax withholdings are excluded. Informational only.

1 Day
-0.69%
5 Days
-0.67%
1 Month
-7.60%
6 Months
+22.84%
1 Year
+73.40%

$KRYS stock is featured in our Insider Score Rankings, and Insider Trades datasets.

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Recently reported changes in KRYS holdings by institutional investors

Scanning latest 13F filings…

Latest 0 13F filings · Source: SEC EDGAR

View all institutional owners →

Insider Trading

Quarterly net insider trading by KRYS's directors and management

Net Shares Purchased by Insiders−70k−35k02025Q42026Q12026Q22026Q32026Q4

Source: SEC EDGAR (Form 4)

Corporate Lobbying

KRYS Estimated quarterly lobbying spending

Source: U.S. Senate LDA

KRYS Revenue by Segment

$126.88MTotal
SegmentRevenue% of All
Product revenue, net$119.22M93.96%
Interest and other income, net$7.66M6.04%

As of: Q2 2026 (Jun 30, 2026) · Source: SEC EDGAR (10-Q)

U.S. Patents

New KRYS patent grants

Loading patent grants…

Source: USPTO Open Data Portal

Government Contracts

Estimated quarterly amount awarded to KRYS from public contracts

Source: USAspending.gov

Top ETF Holders

ETFs with the largest estimated holdings in KRYS

ETFEst. Holding Size
VTIVanguard Morningstar Total Stock Market ETF$320.34M
VBVanguard Morningstar Small-Cap ETF$231.59M
IWMiShares Russell 2000 ETF$222.45M
XBIState Street SPDR S&P Biotech ETF$145.31M
VBKVanguard Morningstar Small-Cap Growth ETF$132.90M
VXFVanguard Extended Market ETF$109.54M

Estimated from each fund’s disclosed top holdings × AUM

KRYS Insider Score

Our composite score: insider buying, sector, volume, tone & dilution

Members only

The live Insider Score for KRYS is included with Insider Access.

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Bull Case vs Bear Case

AI-generated from KRYS’s recent data — informational, not investment advice

Generating analysis…

Insider Score

Our 0–100 Insider Score and the signals behind it.

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Recent Insider Activity

Buys
0
Sells
31
Buy Value
$0
Distinct Buyers
0

Frequently Asked Questions

Disclaimer — Informational only — not investment advice. Insider transaction data is sourced from SEC Form 4 filings; market data from public feeds and may be delayed. The Insider Score is a proprietary score for research purposes and does not predict future performance. Always do your own research.
Krystal Biotech, Inc. (KRYS) Insider Trading, Form 4 Buys & Sells | InsiderBuying.com